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View corresponding page on italian website CURASEPT.IT
Curasept Biosmalto

A UNIQUE APPROACH

BIOMIMETIC ACTIVITY

 

The functional substances of Curasept Biosmalto have chemical, physical, morphological and mechanical properties similar to the biological structures present in nature (enamel and dentin) and can stimulate, in a physiological environment, processes similar to those occurring in the presence of natural biological tissue, such as remineralisation.

BIOCOMPATIBILITY

 

Curasept Biosmalto accomplishes a specific biomedical application without causing toxic effects on the biological system.

BIOACTIVITY

 

Curasept Biosmalto has the ability to chemically interact with the hard tissues of the tooth, depositing a new mineral phase in continuity with the pre-existing one.

3 PATENTS

Icona Biosmalto mouthwashes and toothapstes

Biomimetic technology thanks to the mixture of HYDROXIAPATITIS:

  • Partially substituted hydroxyapatite
    with Magnesium, Strontium and Carbonate conjugated with Chitosan. Chitosan’s affinity for enamel facilitates the release of active ions directly onto tooth surfaces.
  • Hydroxyapatite partially replaced
    with Fluorine.
CARBONATE

able to make the active ions bioavailable

MAGNESIUM

promotes nucleation

STRONTIUM

stabilizes the newly formed mineral phase

CHITOSAN

prolongs the release of active components

FLUORIDE

strengthens the newly formed mineral phase

Click On the Component

CARBONATE

able to make the active ions bioavailable

MAGNESIUM

promotes nucleation

STRONTIUM

stabilizes the newly formed mineral phase

CHITOSAN

prolongs the release of active components

FLUORIDE

strengthens the newly formed mineral phase

The two functional substances contained in both toothpastes and mouthwashes enable a NEW MINERAL PHASE THAT IS MORE RESISTANT to acid attacks and mechanical strains. Therefore, their application increases resistance to caries, inhibits the formation of bacterial plaque, stimulates the remineralization of enamel and dentin, protects against acid erosion and also, thanks to the presence of Strontium salts, reduces the symptoms of dentine sensitivity.
Icona Biosmalto shock action mousse

Bio-inspired Technology:

  • Amorphous calcium phosphate nanoparticle enriched with carbonate and fluorine. Outer layer is made of citrate.
  • Amorphous Calcium Phosphate Phase – ACP – functionalized with Fluorine, Carbonate coated with Citrate. Amorphous Calcium Phosphate (ACP) is a highly reactive, non-crystalline material that rapidly converts to hydroxyapatite: in nature it is the precursor of enamel and dentin.
CARBONATE

increases the solubility of the complex and the bioavailability of the active ions: Calcium, Phosphate and Fluoride.

CITRATE

essential for maintaining healthy and strong teeth, externally coats F-ACP particles, stabilizes and makes the complex more biomimetic.

FLUORIDE

present in free form within the complex, it contributes to the formation of Fluoroapatite.

Caries Abrasion & Erosion

It acts effectively on the damage caused by
abrasion and erosion and creates a new
stronger mineral phase.

REMINERALIZATION
TO THE NTH DEGREE

Sensitive Teeth

Creates a new mineral phase that is more resistant to acid attacks.
Quickly reduces sensitivity.

SENSITIVITY
DAYS ARE NUMBERED.

Baby Kid and Junior

Curasept Biosmalto Age of Development (Baby-Kid-Junior) products are designed to act in the optimal way with respect to the degree of development of the dental system, but also in total physiological respect for the person, because each age has different needs. The range is extensive (toothpastes and toothbrushes) and accompanies children through growth to adulthood with solutions differentiated by age and Fluoride concentrations.

DISCOVER THE FULL RANGE

at home strong action mousse and pack Curasept Biosmalto Caries Abrasion Erosion mint and strawberry flavours
CURASEPT BIOSMALTO MOUSSE CARIES ABRASION & EROSION (HOME TREATMENT)
strong action mousse for home use and pack Curasept Biosmalto Sensitive Teeth
CURASEPT BIOSMALTO MOUSSE FOR SENSITIVE TEETH (HOME TREATMENT)
mouthwash and pack Curasept Biosmalto Caries Abrasion Erosion
CURASEPT BIOSMALTO MOUTHWASH CARIES ABRASION & EROSION
Mouthwash and packaging Curasept Biosmalto Sensitive Teeth
CURASEPT BIOSMALTO MOUTHWASH SENSITIVE TEETH
CURASEPT BIOSMALTO PROBIOTIC FOOD SUPPLEMENT
CURASEPT BIOSMALTO TOOTHBRUSH BABY
CURASEPT BIOSMALTO TOOTHBRUSH KID
CURASEPT BIOSMALTO TOOTHBRUSH PROTECTION
CURASEPT BIOSMALTO TOOTHBRUSH PROTECTION JUNIOR
CURASEPT BIOSMALTO TOOTHBRUSH SENSITIVE
toothpaste and pack Curasept Biosmalto Caries Abrasion Erosion
CURASEPT BIOSMALTO TOOTHPASTE CARIES ABRASION & EROSION
Toothpastes and packaging Curasept Biosmalto Baby Kid 6 months- 6 years strawberry and mint flavour
CURASEPT BIOSMALTO TOOTHPASTE CARIES ABRASION & EROSION BABY – KID (6 months – 6 years)
toothpaste and pack Curasept Biosmalto Caries Abrasion Erosion Baby Without Fluoride Strawberry Flavour
CURASEPT BIOSMALTO TOOTHPASTE CARIES ABRASION & EROSION BABY – KID NO FLUORIDE
toothpaste and pack Curasept Biosmalto junior all fruit flavour
CURASEPT BIOSMALTO TOOTHPASTE CARIES ABRASION & EROSION JUNIOR (7 - 12 years)
toothpaste and pack Curasept Biosmalto sensitive teeth
CURASEPT BIOSMALTO TOOTHPASTE SENSITIVE TEETH

THE FIRST NON-STAINING CHLORHEXIDINE

The first Curasept mouthwashes and toothpastes with Chlorhexidine featuring A.D.S.® – Anti Discoloration System, an innovative, patented, and clinically tested system that reduces the appearance of yellow-brown spots on the teeth, which is the main side effect of Chlorhexidine.

A.D.S.® inhibits the two chemical reactions leading to pigmentation, without affecting the antiplaque activity of Chlorhexidine. 

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Quality Policy

The Quality for CURASEPT S.p.A. is an essential condition to put itself successfully on the market, considering its characteristics and evolution.

The development of the Company and its profit are insured by the continuous search for quality towards excellence through the continuous improvement of its processes and the search for partners with quality systems adapted to our standards.

The Company aims to increase the customer satisfaction through the application of its Quality Management System, including the processes to improve the system and to ensure the compliance with the customer and applicable regulatory requirements.

For this purpose, the Company performs specific risks and opportunities assessment activities, connected to the context, stakeholders and related objectives, in order to identify the areas of system improvements and to define the appropriate actions for the risk control and mitigation and strengthening of its Quality System.

The starting point for the implementation of this policy is the pursuit of the following objectives:

  • Define and implement a Quality Management System according to 9001:2015+A1:2024 e UNI CEI EN ISO 13485:2021 regulation, as Manufacturer of Medical Devices;
  • Define and implement a system of procedures and operating instructions in harmony with the Directive 93/42/CEE, the Regulation (UE) 2017/745 and the Regulation (UE) 2023/607 for the applicable parts and subsequent changes and integrations, which satisfy the essential requirements set out in Annex I;
  • Define and implement a system of procedures in harmony with the Directive 2010/84, the Regulation 1235/2010, the Implementation Regulation n. 520/2012 and in accordance with the objectives of “module I – “Good Vigilance Practices” (GVP);
  • Establish and formalize the business organizational structure with the subdivision into areas of competences;
  • Clarify roles and responsibilities of business functions;
  • Define strategies and objectives and assign human and material resources for their achievement;
  • Define accurately business processes and related performance factors;
  • Ensure compliance with qualitative, quantitative and temporal requirements;
  • Constantly monitor the level of adequacy of the system with reference to regulations and laws;
  • Promote initiatives in order to improve the process of motivational and professional growth of human resources, considered as critical resources for future business developments;
  • Ensure the commitment to the satisfaction of requirements and the maintenance of effectiveness of the Quality Management System.

These objectives can be realized thanks to the involvement of the whole Company personnel.

In particular, the Managers of each Function provide their contribution so that the suggested improvements can be proposed to the General Direction, so that the Quality Policy can be a priority element in the choice of business qualitative and organizational strategies.

The involvement of the whole personnel in the improvement of internal and external processes should be aimed at reducing non-compliance and internal and external costs of non-quality; for this reason all employees should feel themselves committed in pursuing this policy.

Training courses, for all business levels, are promoted and planned by the General Direction in order to keep the personnel constantly up to date on the improvements performed for the processes.

The Quality Manual, which is distributed via the SistemaQualità to all process managers and the General Director, should represent a work tool for all Managers and their personnel for the implementation of the Quality Policy.

April 2025

General Direction